Toxicity is the second studio album by the heavy metal band System of a Down, released in September 2001. Expanding on their 1998 eponymous debut album, Toxicity incorporates more melody, harmonies, and singing than the band's first album.

The album features elements of multiple genres, including folk, progressive rock, jazz, and Armenian and Greek music, including prominent use of instruments like the sitar, banjo, keyboards, and piano. It contains a wide array of political and non-political themes, such as mass incarceration, the CIA, the environment, police brutality, drug addiction, scientific reductionism, and groupies.